Detalhe da pesquisa
1.
Global and cell type-specific immunological hallmarks of severe dengue progression identified via a systems immunology approach.
Nat Immunol
; 24(12): 2150-2163, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37872316
2.
Single B cell transcriptomics identifies multiple isotypes of broadly neutralizing antibodies against flaviviruses.
PLoS Pathog
; 19(10): e1011722, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37812640
3.
Nonlytic cellular release of hepatitis A virus requires dual capsid recruitment of the ESCRT-associated Bro1 domain proteins HD-PTP and ALIX.
PLoS Pathog
; 18(8): e1010543, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35969644
4.
The cargo adapter protein CLINT1 is phosphorylated by the Numb-associated kinase BIKE and mediates dengue virus infection.
J Biol Chem
; 298(6): 101956, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35452674
5.
Identification and evaluation of 4-anilinoquin(az)olines as potent inhibitors of both dengue virus (DENV) and Venezuelan equine encephalitis virus (VEEV).
Bioorg Med Chem Lett
; 52: 128407, 2021 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34624490
6.
Virus-inclusive single-cell RNA sequencing reveals the molecular signature of progression to severe dengue.
Proc Natl Acad Sci U S A
; 115(52): E12363-E12369, 2018 12 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30530648
7.
Optimization of 4-Anilinoquinolines as Dengue Virus Inhibitors.
Molecules
; 26(23)2021 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34885921
8.
Potent antiviral activity of novel multi-substituted 4-anilinoquin(az)olines.
Bioorg Med Chem Lett
; 30(16): 127284, 2020 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32631507
9.
Structure-activity relationship study of the pyridine moiety of isothiazolo[4,3-b]pyridines as antiviral agents targeting cyclin G-associated kinase.
Bioorg Med Chem
; 28(1): 115188, 2020 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31757682
10.
Epidermal Growth Factor Receptor-Dependent Mutual Amplification between Netrin-1 and the Hepatitis C Virus.
PLoS Biol
; 14(3): e1002421, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-27031829
11.
Viral journeys on the intracellular highways.
Cell Mol Life Sci
; 75(20): 3693-3714, 2018 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-30043139
12.
Pathogen receptor discovery with a microfluidic human membrane protein array.
Proc Natl Acad Sci U S A
; 113(16): 4344-9, 2016 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27044079
13.
AP-2-associated protein kinase 1 and cyclin G-associated kinase regulate hepatitis C virus entry and are potential drug targets.
J Virol
; 89(8): 4387-404, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25653444
14.
B-cell receptors expressed by lymphomas of hepatitis C virus (HCV)-infected patients rarely react with the viral proteins.
Blood
; 123(10): 1512-5, 2014 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-24449209
15.
Identification and targeting of an interaction between a tyrosine motif within hepatitis C virus core protein and AP2M1 essential for viral assembly.
PLoS Pathog
; 8(8): e1002845, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22916011
16.
Chemical inactivation strategies for SARS-CoV-2-infected cells and organoids.
STAR Protoc
; 5(1): 102906, 2024 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38401122
17.
Systems immunology of transcriptional responses to viral infection identifies conserved antiviral pathways across macaques and humans.
Cell Rep
; 43(2): 113706, 2024 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38294906
18.
An orally bioavailable SARS-CoV-2 main protease inhibitor exhibits improved affinity and reduced sensitivity to mutations.
Sci Transl Med
; 16(738): eadi0979, 2024 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38478629
19.
Back-pocket optimization of 2-aminopyrimidine-based macrocycles leads to potent dual EPHA2/GAK kinase inhibitors with antiviral activity.
bioRxiv
; 2024 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38405908
20.
PIP4K2C inhibition reverses autophagic flux impairment induced by SARS-CoV-2.
bioRxiv
; 2024 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38659941